Lobotomy

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Lobotomy refers to the act of exiling all (or any) copies of a card generally from target player's hand, library and graveyard. It alludes to the effect of its namesake, the Tempest card Lobotomy.[1]

Lobotomy effects are primary centered in black—flavored as permanently messing with people's minds. Blue also used to be getting a decent amount, but nowadays it is solely to be found in black.[2] Urza's Destiny had a lobotomy cycle that was reprinted in Betrayers of Kamigawa.

The most famous cards are Extirpate and Surgical Extraction.

Last Updated for Modern Horizons 3

Lobotomy cards are

Name Cost Original Set What being lobotomized
Counterbore {3}{U}{U} Shadowmoor Lobotomizes a countered spell.
Cranial Extraction {3}{B} Champions of Kamigawa Lobotomizes a nonland card of chosen card name.
Crumble to Dust {3}{R} Battle for Zendikar Lobotomizes a nonbasic land.
Deicide {1}{W} Journey into Nyx Lobotomizes an enchantment if it's also a God.
Dispossess {2}{B} Amonkhet Lobotomizes an artifact of chosen card name.
Eradicate {2}{B}{B} Urza's Destiny Lobotomizes a nonblack creature.
Extirpate {B} Planar Chaos Lobotomizes a chosen card, other than a basic land, from a graveyard.
Haunting Echoes {3}{B}{B} Odyssey Lobotomizes all cards, others than a basic land, from a graveyard.
Infinite Obliteration {1}{B}{B} Magic Origins Lobotomizes a creature of chosen card name.
Invasive Surgery {U} Shadows over Innistrad Lobotomizes a countered sorcery spell if the player has enabled Delirium.
Lobotomy {2}{U}{B} Tempest Lobotomizes a chosen card, other than a basic land, from a hand.
Lost Legacy {1}{B}{B} Kaladesh Lobotomizes a nonartifact, nonland card of chosen card name.
Memoricide {3}{B} Scars of Mirrodin Lobotomizes a nonland card of chosen card name.
Pick the Brain {2}{B} Shadows over Innistrad Lobotomizes a chosen nonland card from a hand if the player has enabled Delirium.
Quash {2}{U}{U} Urza's Destiny Lobotomizes a countered instant or sorcery spell.
Reap Intellect {X}{2}{U}{B} Dragon's Maze Lobotomizes chosen up to X nonland cards from a hand.
Scour {2}{W}{W} Urza's Destiny Lobotomizes an enchantment.
Shimian Specter {2}{B}{B} Future Sight Creature that lobotomizes a chosen nonland card from a hand when deals combat damage to that hand's player.
Slaughter Games {2}{B}{R} Return to Ravnica Lobotomizes a nonland card of chosen card name.
Sowing Salt {2}{R}{R} Urza's Destiny Lobotomizes a nonbasic land.
Splinter {2}{G}{G} Urza's Destiny Lobotomizes an artifact.
Stain the Mind {4}{B} Magic 2015 Lobotomizes a nonland card of chosen card name.
Surgical Extraction {B/P} New Phyrexia Lobotomizes a chosen card, other than a basic land, from a graveyard.
Thought Hemorrhage {2}{B}{R} Alara Reborn Lobotomizes a nonland card of chosen card name.
Silver-bordered
Name Cost Original Set What being lobotomized
Look at Me, I'm the DCI {5}{W}{W} Unglued Lobotomizes a card of chosen card name to all players (including their sideboards and the battlefield). The exiled cards remain exiled until the match ends.

References