Church of Avacyn
The symbol that represents the religion of humanity on Innistrad is the Church of Avacyn. The central figure of the church is Avacyn itself, an archangel so pure and an extremely powerful that contained Innistrad darkness.
Until recently, the presence of Avacyn was so decisive that faith in her gave it real power to the clergy and other faithful, a power stepped back creatures of evil. The blessed silver weapons could destroy the worst horrors and very powerful runes marked with her symbol protected entire villages. The effectiveness of the church was concrete and visible, a welcome weapon in a world of atrocities.
However, the Archangel Avacyn has not been seen in several seasons, and his absence is starting to be felt with the advancement of darkness. Since Avacyn has disappeared, the prayers were not enough to prevent terrible attacks of werewolves to remote villages. Sacred symbols were unable to stop the vampires from taking advantage of travelers passing through the mountains. The dead are not protected against tampering and resuscitation of the flesh ... alchemists, necromancers and ghoulcallers now act carelessly.
Not even the elders of the church, including Mikaeus, the "Ruling Lunarch" have said a word about what may have happened to Avacyn.
Can it be definitive that Avacyn is gone? What used to be the most powerful weapon in the struggle for survival of mankind, today has abandoned them, leaving the Church powerless to contain the dark forces of Innistrad.